Like the aglets at the end of your shoelaces, protein-and-DNA assemblies known as telomeres protect the ends of your chromosomes from fraying. In work with potential implications for the development ...
DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many ...
A collaboration led by Distinguished Professor Dr. Kazunori Ikebukuro from Tokyo University of Agriculture and Technology (TUAT), Japan, discovered that G-quadruplex (G4)-forming DNA binds myoglobin ...
A team of investigators at Carnegie Mellon University has formed the first hybrid quadruplex of peptide nucleic acids, or PNAs, with DNA, the genetic code. This result opens new opportunities to study ...
Researchers have discovered a novel set of MYC promoter G-quadruplex stabilizers that have demonstrated anticancer activity in human cancer cell cultures. A gene called MYC has become one of the ...
Most women with ovarian cancer respond very well to chemotherapy at first – but in 70% of cases the cancer grows back. And although many patients will respond to chemotherapy a second or third time, ...
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