DNA transcription and mRNA processing
10:25
Khan AcademySal Khan
DNA transcription and mRNA processing
Transcription involves rewriting genetic information from DNA to mRNA, with RNA polymerase playing a crucial role. In eukaryotic cells, DNA to mRNA transcription occurs within the nucleus, producing pre-mRNA. This pre-mRNA undergoes processing, including the addition of a 5' cap, a poly-A tail, and splicing out introns, resulting in mature mRNA ...
Jun 7, 2016
MRNA Vaccine Production
🧬✨Reimagining Parasite Control with mRNA Technology Building on the mRNA revolution sparked by the COVID-19 pandemic, this project developed a first-in-class mRNA vaccine candidate against Ancylostoma ceylanicum—a parasitic helminth affecting humans and animals. From plasmid DNA production and mRNA synthesis to lipid nanoparticle formulation, the vaccine showed successful antigen expression and promising immunogenicity, safety, and stability. 🚀 This work lays the foundation for scalable mRNA v
0:54
🧬✨Reimagining Parasite Control with mRNA Technology Building on the mRNA revolution sparked by the COVID-19 pandemic, this project developed a first-in-class mRNA vaccine candidate against Ancylostoma ceylanicum—a parasitic helminth affecting humans and animals. From plasmid DNA production and mRNA synthesis to lipid nanoparticle formulation, the vaccine showed successful antigen expression and promising immunogenicity, safety, and stability. 🚀 This work lays the foundation for scalable mRNA v
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